Control of hepatic gluconeogenesis through the transcriptional

Gluconeogenesis is not simply the reverse of glycolysis; it utilizes unique enzymes (pyruvate carboxylase, PEPCK, fructose-1,6- bisphosphatase, and glucose-6-

Brain and muscle consume most of the glucose • Liver and kidney are the main sites of gluconeogenesis • Substrates include pyruvate, lactate, glycerol, most

gluconeogenesis Gluconeogenesis is a metabolic pathway that results in the generation of glucose from non-carbohydrate carbon substrates such as lactate,

gluconeogenesis The first step of gluconeogenesis that bypasses an irreversible step of glycolysis, namely the reaction catalyzed by pyruvate kinase, is the